They found that the most common pattern was for the activity to be the same at all three observational points, whether the enzymatic period was during exonuclease repair or DNA extension. “This ...

6 A combination of highly processive thermostable DNA polymerase and a high-fidelity polymerase with 3′-5′ exonuclease activity helps achieve long-range PCR. 7 This allows the amplification of long ...

As a DNA sample is introduced, the exonuclease functions to 'capture' the DNA molecule and direct the sequentially cleaved bases through the nanopore. As each cleaved base traverses the nanopore ...