In particular, it explains that humans have one fewer chromosome pair in their cells than apes, due to a mutation found in chromosome number 2 that caused two chromosomes to fuse into one.

Johan Gibcus, PhD, assistant professor of systems biology and co-first author on the study explained, “We found that these machines extrude loops and as they do so they race along the chromosomes at ...

We previously reported suggestive linkage between type 2 diabetes and markers in a region on chromosome 20q using data from a collection of 29 Caucasian families in which type 2 diabetes with ...

According to Dr. Gibcus, during the mitotic phase of cell division, four different loop-extruding machines are acting simultaneously along the chromosomes: two types of cohesin machines and two ...

Naturally occurring dicentric chromosomes allow examination of complex cis–acting effects that regulate kinetochore function and chromosome segregation. Dicentric chromosomes with well ...