High blood pressure, or hypertension, affects more than a billion people worldwide and remains the leading cause of death due ...

Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...

Cardiovascular diseases are the world's leading cause of death, and high blood pressure, or hypertension, affects more than 1 ...

Medically reviewed by Alex Yampolsky, PharmD Your kidneys are responsible for filtering waste and excess fluid from the blood ...

The potential benefit of angiotensin II-receptor antagonism is not limited to well-tolerated blood pressure control. Angiotensin II has complex effects on the heart and kidneys. Blocking the ...

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Angiotensin II ist ein zu den Gewebshormonen zählende Peptidhormon, bestehend aus acht Aminosäuren (Oktapeptid). Es nimmt die Schlüsselposition in dem für die Aufrechterhaltung des Blutdrucks und des ...

The dual-action agent LCZ696 blocks the angiotensin II receptor (via a valsartan moiety) and inhibits neprilysin (via an AHU377 moiety). In a phase II trial, this drug “demonstrated superior ...

Adults recently diagnosed with immunoglobulin A nephropathy who were assigned sparsentan as first-line therapy experienced rapid and sustained reductions in proteinuria, according to ...

Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu Angiotensin I Asp-Arg-Val-Tyr-Ile-His-Pro-Phe Angiotensin II David W. Cushman In 1967, John Vane, a consultant at The Squibb Institute for Medical Research ...

HFrEF-- Nationale und internationale Leitlinien empfehlen den Angiotensin-Rezeptor-Neprilysin-Inhibitor (ARNI)a als eine ...