Cardiovascular diseases are the world's leading cause of death, and high blood pressure, or hypertension, affects more than 1 ...

Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...

Medically reviewed by Alex Yampolsky, PharmD Your kidneys are responsible for filtering waste and excess fluid from the blood ...

The potential benefit of angiotensin II-receptor antagonism is not limited to well-tolerated blood pressure control. Angiotensin II has complex effects on the heart and kidneys. Blocking the ...

Angiotensin II ist ein zu den Gewebshormonen zählende Peptidhormon, bestehend aus acht Aminosäuren (Oktapeptid). Es nimmt die Schlüsselposition in dem für die Aufrechterhaltung des Blutdrucks und des ...

The dual-action agent LCZ696 blocks the angiotensin II receptor (via a valsartan moiety) and inhibits neprilysin (via an AHU377 moiety). In a phase II trial, this drug “demonstrated superior ...

Adults recently diagnosed with immunoglobulin A nephropathy who were assigned sparsentan as first-line therapy experienced rapid and sustained reductions in proteinuria, according to ...

HFrEF-- Nationale und internationale Leitlinien empfehlen den Angiotensin-Rezeptor-Neprilysin-Inhibitor (ARNI)a als eine ...

Arbli, an angiotensin II receptor blocker, is indicated for the treatment of hypertension, to lower blood pressure in adults and children greater than 6 years old; for the reduction of the risk of ...