These groups commonly made use of multiple sequence alignments, alignment of actual and predicted secondary structures and hand–adjustments. Knowing the structure of a protein is useful for ...

Other specific factors include the sequence similarity in the structural alignment and the amount of common structure shared by the target protein and the protein of most similar known structure.

Sarika Kondra and her co-author's TSR-based method represents a major advancement in protein structure analysis, integrating ...

Proteins have evolved to minimize energetic conflicts between their parts, so they can be funneled toward their static structure ... the input multiple sequence alignment sequences that encode ...

nephronophthisis 2-a gene linked to kidney disease that also affects cilia-made the alignment worse. When a third gene, histone deacetylase 6, which helps regulate proteins and cell structure, was ...