Additionally, the Incucyte ® Spheroid software module functions as a high-speed, adaptable and effective control hub for continuous live-cell analysis incorporating the complete image acquisition ...

1, 2 As the accessibility of 3D spheroid protocols rises, the experimental models are becoming more complicated with greater translational potential, frequently including further components that ...

A direct indicator of the anticancer effect of a candidate drug is a reduction in the size of the cancer spheroid. Given that most spheroids are not perfectly spherical, size is best measured using a ...

We discuss essential conceptual and practical considerations for an adequate establishment and use of spheroid-based drug screening platforms and also provide a list of human carcinoma cell lines ...

In recent year’s 3D spheroid cultures have come to the fore particularly in the areas of cancer research, drug discovery and toxicology, mainly because they are amenable to generation in large numbers ...

Instead of attempting to isolate and sort individual lung stem cells or genetically convert other types of cells into lung stem cells, Cheng used a multicellular spheroid method to harvest and ...

In basic and applied biology research, such as investigations of stem cells and drug screening, spheroid cell cultures are valuable, providing a more realistic test environment than the 2D cultures ...

The implementation of 3D spheroid culture plays an important role as an alternative approach for drug development and therapeutic applications in central neural system (CNS) disorders. To develop a ...