The structural characterization of complex proteins gives researchers a glimpse into their in vivo mechanistic functions and complex chemistries. In the case of drug development, structural ...

Size exclusion chromatography (SEC ... the resolution and increase in column diameter results in high bed volume and hence higher column capacity. The fractionation range and the exclusion ...

Selectivity is based on biomolecule size. SXC behaves like a rapid high-capacity alternative to size exclusion ... a 10-bed volume linear gradient to 100% B. Protein A affinity chromatography ...

A subset of high performance liquid chromatography (HPLC), size exclusion chromatography (SEC ... In this method, polymer molecules are isolated depending on their hydrodynamic volume. To explain this ...

Conventionally, such information is obtained using size exclusion chromatography (SEC) techniques, where the identification of sample components is based on molecular weights. The identification of ...

were analyzed by size exclusion chromatography with triple detection. The black line shows the refractive index, while the red line showed the molecular mass, plotted as an elution volume function.

Size-exclusion liquid chromatography (SEC) has been the preferred method for detecting and quantifying AAV aggregates. SEC is a non-interacting, passive separation chromatographic technique utilizing ...

To solve this problem, we present kinetic size-exclusion chromatography with mass spectrometry detection (KSECMS), a solution-based label-free approach. KSEC-MS utilizes the ability of size ...