SG-NEx provides an open-access resource for the global research community, accelerating biomarker discovery and precision medicine through: Singapore – A team of scientists led by the A*STAR Genome ...

One such chemical modification is cytidine acetylation (N4-acetylcytidine). Until now, the precise function of this chemical modification within cells has not been clearly understood. In particular, ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

A new national programme that aims to position Singapore at the forefront of advancements in RNA science and applications was officially launched today. This new initiative – named National Initiative ...

New research published in Nature has uncovered powerful evidence that may explain why a new chemical modification of RNA is made in cells. Subscribe to our newsletter for the latest sci-tech news ...

University of Chicago researchers have developed a liquid biopsy test based on modification patterns in microbiome-derived cell-free RNA that predicts colorectal cancer (CRC) with greater accuracy ...

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A ...

To overcome these limitations, the research team developed a "targeted RNA acetylation system (dCas13-eNAT10)" by combining Cas13, gene scissors that precisely target desired RNA, with a hyperactive ...