The purine structure consists of a pyrimidine ring (positions 1 to 6) fused to an imidazole ring (positions 7 to 9). Adenine and guanine, the two most common purines in DNA and RNA, share this core ...

Within the canonical class of fluorescent nucleobases, chemical modifications have been employed on both purine and pyrimidine structures. Ring fusion, ring structure modification as well as ...

Chemical structure of guanine, showing its double-ring purine structure and the functional groups involved in hydrogen bonding with cytosine. (Image: Public Domain) Guanine has the chemical formula ...

Here we demonstrate that structure-based development and iterative ... The planes of the purine and anilino rings are tilted relative to each other with an interplanar angle of 50°.

guanosine nucleoside analog that mimics other purines, including inosine and adenosine. Structure-activity relationship studies reveal that the 1,2,4-triazole ring, carboxamide group, and beta-D ...