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Scientists expand the genetic alphabet to create new proteins"Our goal is to develop proteins with tailored functions ... But many amino acids have more than one possible codon; for instance, RNA reading the sequences UAU and UAC both correspond to the ...
“Our goal is to develop proteins with tailored functions ... However, many amino acids have more than one possible codon; for instance, RNA reading the sequences UAU and UAC both correspond ...
Gene sequences are made up of nucleotide bases, which are 'read' by the cell's machinery in triplets; three nucleotide bases are interpreted as one codon, and every codon ... genome are long repeats ...
To understand why repurposing the TCG codon minimally affected other proteins in the cell, Lin’s team studied the RNA sequences on either side of the TCG codon. They found that the efficiency of ...
To synthesize functional proteins and avoid toxic translation products, the recognition of the correct initiation codon (AUG ... turn affect the evolution of sequences downstream of aATG.
A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...
with one stop codon — using a cellular platform that they developed enabling the production of new classes of synthetic proteins. These synthetic proteins, researchers say, offer the promise of ...
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