KirBac channels are prokaryotic homologs of mammalian inwardly rectifying (Kir) potassium channels ... conformation and determined the crystal structure of this mutant channel to 3.05 Å resolution.

Figure 1: BK channel structure and specific potassium permeability. Two-thirds of the SLO protein sequence forms the large cytoplasmic C-terminal domain; we therefore assign the large particle ...

“BK is the first potassium channel I studied, so it is enormously satisfying to finally observe its molecular structure,” concluded MacKinnon. Below, check out an interview with him from earlier this ...

Defective potassium channels play a role in epilepsy and depression. Scientists have now identified the complete 3D structure of a particular potassium channel, a HCN channel. This enabled them to ...

Since 1998, Roderick MacKinnon, head of molecular neurobiology and biophysics, Rockefeller University, and Howard Hughes Medical Institute (HHMI) investigator, and colleagues have published papers ...

The image illustrates the structure of a potassium ion channel including the cytosolic domain (CTD), colored cyan, which is ...

opening in response to changes in membrane voltage and allowing potassium ions to escape. Hodgkin and Huxley laid out a model in 1952 for what voltage-gated channels might be doing, but their ...

Researchers have revealed the structure and function of a potassium ion channel in fruit flies. Their newly obtained insights reveal the differences between human and insect channels, explain how ...

Potassium channel blockers are a type of medication used to treat conditions like cardiac arrhythmias. They block the movement of potassium channels in the body, disrupting the body’s electrical ...

In Arabidopsis, the outward-rectifying potassium channel GORK drives potassium ... More information: Xue Zhang et al, GORK K+ channel structure and gating vital to informing stomatal engineering ...

joined forces with protein manufacturing company Cube Biotech and Bayer's Crop Science division to reveal the structure and function of a potassium ion channel from fruit flies. Their newly ...