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Mechanochemistry strikes again: Solvent-free method simplifies synthesis of organolithium moleculesSeveral established synthetic routes towards organolithium compounds require relatively complex reaction set-ups, large quantities of organic solvent, and strict attention towards air, moisture ...
and organolithium reagents (RLi) are strong nucleophiles that can add to electrophilic carbon atoms, particularly in carbonyl groups. Example: Reaction of a Grignard reagent with a carbonyl compound.
The findings are published in Nature Protocols. In this study, the researchers demonstrated the initiation of polymerization reactions, such as reversible addition–fragmentation chain transfer ...
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