In recent years, overweight and obesity have become a serious global health problem, posing significant risk factors for ...

Samples were obtained from C57Bl/6 mice aged 16 weeks. We studied the ob/ob genetically obese mouse model and diet-induced obesity model. We extended our results in mice to a cohort of morbidly ...

Halofuginone can regulate appetite and energy metabolism by increasing the levels of growth differentiation factor 15 (GDF15) ...

Leptin-deficient (ob/ob) mice are obese and infertile. Dysfunctions of the ovaries are preferentially related to leptin-deficiency. Ovaries were obtained from three-month-old mice either ...

Eight-week-old female ob/ob mice received daily intraperitoneal injections of vehicle (six mice), 0.2 μg of nonmutant leptin per gram of body weight (six mice), or 0.2 μg of D100Y leptin per ...

They also conducted similar experiments on ob/ob mice that were genetically programmed to exhibit leptin dysfunction. Leptin—a hormone synthesized by fat cells—controls satiety and energy ...

In that study, the researchers used the 3D data to identify changes in the Islets of Langerhans in the obese (ob/ob) mice. This animal model is often used to study initial metabolic changes that ...

They also conducted similar experiments on ob/ob mice that were genetically programmed to exhibit leptin dysfunction. Leptin - a hormone synthesized by fat cells - controls satiety and energy ...

Share on Pinterest A recent study finds that a failed cancer drug reduces appetite and boosts weight loss in mice. lingqi xie/Getty Images Small doses of a drug once considered for treating tumors ...

As a result, it was found that obese/diabetic model (Ob/Ob) mice had a significantly lower survival rate than wild-type mice. In addition, two days after infection, large amounts of virus were ...