Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...
DNA repair mechanism: HELQ helicase remodels stalled replication forks into stable structures, preventing harmful mutations under replication stress. Advanced imaging tool: RF-SIRF maps reversed forks ...
Origins of the code: University of Illinois researchers found that the genetic code’s origins are tied to dipeptide composition, offering clues to life’s earliest evolution. Beyond coding DNA: Most ...
While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...
From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body’s typically efficient DNA repair machinery and potentially affecting our health ...
Alphabet Inc.’s Google DeepMind today introduced AlphaGenome, a new artificial intelligence tool that can comprehensively predict how mutations or variants in human DNA sequences impact gene ...
The secret to the naked mole-rats' extraordinarily long life may lie in subtle changes to just four amino acids, researchers report. According to a new study, evolutionary mutations in cGAS – an ...
Autoimmune diseases could be driven by DNA mutations in immune cells that remove natural brakes on the immune system, according to a new study that used advanced DNA sequencing methods. Findings ...
Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...