Methotrexate is a primary disease-modifying anti-rheumatic drug (DMARD) used to treat rheumatoid arthritis (RA) by reducing inflammation and suppressing the immune system. The American College of ...

There have been a lot of questions about medical care and treatment in the wake of the overturning of Roe v. Wade, the landmark legislation that previously made abortion legal in the U.S. on a federal ...

Methotrexate injectable intravenous (IV) solution is only available as a generic drug. It doesn’t have a brand-name version. Methotrexate comes in four forms: injectable IV solution, self-injectable ...

METHOTREXATE delay for 1 month after 13 valent pneumococcal conjugate vaccination did not worsen rheumatoid arthritis disease control, structural progression, or treatment escalation over 1 year, ...

Patients who take methotrexate for a variety of immune-mediated inflammatory diseases and pause taking the drug following receipt of a COVID-19 vaccine dose did not have a higher risk of disease flare ...

Tumor necrosis factor (TNF) has a pathogenic role in juvenile rheumatoid arthritis. We evaluated the efficacy and safety of adalimumab, a fully human monoclonal anti-TNF antibody, in children with ...

Since its approval in the late 1980s for the treatment of rheumatoid arthritis (RA), methotrexate has been the yardstick against which all other therapeutic agents against this disease, including the ...

January 28, 2008 — New research shows that high-dose methotrexate is the most effective drug for primary central nervous system lymphoma (PCNSL), with up to 20% of patients achieving a long-term ...

Please provide your email address to receive an email when new articles are posted on . WASHINGTON — An early, 1-year course of methotrexate may prevent anti-citrullinated protein ...

Methotrexate is the most frequently used first-line antirheumatic drug. We report the findings of a phase 3 study of monotherapy with tofacitinib, an oral Janus kinase inhibitor, as compared with ...

Medically reviewed by Scott Zashin, MD Key Takeaways People taking methotrexate should avoid alcohol because it can increase the risk of liver damage.Some NSAIDs like aspirin should not be taken with ...

Methotrexate is a strong medicine. The FDA approved it to treat adults with severe, disabling psoriasis that cannot be controlled with medicine applied to the skin or light treatments. Methotrexate ...