MD Anderson studies reveal how cancer cells rewire metabolism to spread. A glucose–fructose mix promotes colorectal metastasis via cholesterol pathways, while fatty-acid oxidation driven by ACBP ...

Konstanz researchers identify an enzyme that plays a role in the migration of cells in our body—not only during normal tissue formation and wound healing, but also when tumor cells metastasize. This ...

Cell migration is a multistep process essential to various physiological functions, including immune cell movement and embryonic development, as well as pathological conditions like tumor metastasis.

Millions of people worldwide are diagnosed with cancer every year. In advanced tumor diseases, cancer cells detach from the ...

In this review, the authors present recent findings that uncover a previously unappreciated nuclear signaling hub: the PIPn-p53 signalosome. This complex not only modulates AKT activation within the ...