In this way, the mass photometer was able to distinguish between the two types of molecules in a way that was quicker and just as accurate as conventional methods." Given that the full-to-empty ...

High quality samples are key for data reproducibility and reliability. For biophysical protein characterization, quality samples are defined as those containing pure, soluble protein exhibiting ...

CRISPR-Cas systems are widely used in genome engineering applications. They contain RNA-guided ribonucleoprotein (RNP) complexes that selectively modify DNA sequences at any specific location in the ...

A recently-developed technique for measuring the mass of single molecules in solution has the potential to help companies using adeno-associated viruses (AAV) as a vector for gene therapies. That’s ...

Protein oligomerization is central to many cellular processes; however, capturing and characterizing native protein behaviors in solution can be challenging. Mass photometry is especially suited for ...

To permanently access this eBook for free, fill out the short form below. Struggling with AAV and AdV vector analytical characterization and analysis? Mass photometry and macro mass photometry offer ...

Mass photometry is a novel bioanalytical technology that provides insights into the mass distribution of biomolecules in their native state within minutes, without the need for labeling, surface ...

Adeno-associated virus (AAV)-based gene therapies offer life-changing potential for treating genetic diseases, yet high production costs remain a significant barrier. Optimizing these processes is ...

Refeyn, the company behind pioneering mass photometry technology, announces that mass photometry has been recognized by the U.S. Pharmacopeia (USP)—and referenced in the new draft USP general chapter ...

Osaka, Japan – Gene therapy is at the cutting edge of medicine, with exciting new products being developed and used to treat a wide variety of genetic diseases. However, one major roadblock to ...

Biochemical and structural studies of membrane proteins have long been restricted to their isolated soluble domains. This limitation has prevented the study of complexes involving full-length membrane ...