MYC‑driven tumors silence innate immune alarms by clearing R‑loop–derived signals, exposing a new therapeutic angle for targeting MYC without broad inhibition.

The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.

An international research team has succeeded in deciphering a key mechanism that controls the growth of pancreatic cancers.

So, what insight are we left with? “On the highest level,” notes Dr. Eisenman, “this study really demonstrates that a single amino acid substitution in a single protein is enough to predispose the ...

A small molecule that indirectly targets the tough-to-drug MYC gene appears to work against breast and ovarian cancers in mice. In an article published Oct. 25 in the Proceedings of the National ...

The growth protein, MYC, was consistently found with RBM42, which spurs MYC production, in human pancreatic tumors. Above, microscopy for MYC (red) and RBM42 (green) in a representative pancreatic ...

University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a "two-in-one" molecule that can simultaneously turn off two notoriously difficult-to-target ...

MYC family genes are essential for the human organism. According to current knowledge, they regulate the expression of most cellular genes. Misregulation of MYC proteins significantly contributes to ...

A gene called Myc (pronounced 'mick') that is among the most important drivers of cancer in both mice and humans also plays a newly discovered crucial role in aging. A gene called Myc (pronounced ...

The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system. This finding ...