so the neurons don't have their command center, and it happens without stimulation; it just happens on its own," Kaeser said. "This is spontaneous local triggering of dopamine release." ...

As the adage goes 'neurons that fire together, wire together,' but a new article demonstrates that, in addition to response similarity, projection target also constrains local connectivity.

The exact origin of GABAergic (γ-aminobutyric-acid-releasing) interneurons, which are responsible for control the firing of the principal human cortical neurons, has remained unclear. In rodents all ...

Here we show that in freely behaving rats after a long period in an awake state, cortical neurons can go briefly ‘offline’ as in sleep, accompanied by slow waves in the local EEG. Neurons ...

Connectivity mapping revealed a streamlined architecture: nearly 50,000 local neurons feed into 4,500 projection neurons, which transmit visual information to the central brain through 352 ...

Their findings imply local sharing of resources: a local ‘neighborhood’ of synapses. Neurons constantly process information from thousands of synapses. Numerous synapses populate large volumes ...

“Rather than originating from glia, the new dopamine cells came from local, existing mature neurons without passing through a stem cell state,” Dr. Zhang states. “This is a mature-cell-to ...

The brain is solving a global problem, optimizing for survival, and yet neurons must learn from only local information received at their synapses. Furthermore, the brain must "get better" without ...

Before the connectome was available, neuroscientists weren't sure if inhibitory neurons target specific cells in a given network, rather than just affecting local neurons that happen to be in ...

Investigating the activity of multiple single neurons and local field potential in the mPFC of behaving mice, the authors found that genetic ablation of a subtype of GABA-receptors (GABABRs ...