Lysosomes are thought of as cellular organelles that play an important role in recycling proteins and maintaning cells by breaking down stuff that isn’t needed. But new research has found that ...

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called ...

What role do lysosomes play in cells, and how does lysosomal vacuolation affect their function? Lysosomes are essential for cell health. Like a waste disposal system, they digest damaged proteins, ...

Researchers identified TBC1D9B as the off switch for ARL8B, a key regulator of lysosome positioning. This mechanism controls how cells adapt to nutrient stress and maintain metabolic balance.

Lysosomes are the control centers for the metabolism of cells and tissues, including the brain. They break down defective proteins and other macromolecules into their basic building blocks.

Lysosomes were once viewed mainly as cellular waste disposers, but are now recognized as key hubs for nutrient sensing and ...

Aging is a fact of life. As we get older, our bodies and minds change, and our bodies become susceptible to a number of age-related diseases. As a result, a major focus of scientific research today is ...

Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break ...

Common variants in the phosphoinositol phosphatase INPP5D are linked to an increased risk of late-onset Alzheimer’s disease, but no one is quite sure why. Recent work suggests that depleting INPP5D in ...