A recent study In Press at the Journal of Cell Biology reports that herpes simplex virus 1 (HSV-1) exploits heterochromatin to successfully exit the nucleus. The heterochromatin markers macroH2A1 and ...

Ongoing research aims to confirm the mechanism by which ICP4 fluidizes the nucleus, which could indicate specific targets to counter viral replication.

A new combination of microscopy methods has revealed exquisite detail of the virus assembly process used by herpes simplex virus during replication. The research, published today as a Reviewed ...

Over the last century, humans have experienced multiple severe viral outbreaks, including the Spanish flu and other influenza epidemics, HIV, SARS-CoV, MERS, Ebola, and the recent SARS-CoV2 pandemic.

(A) Cryo-EM structure overview of HSV-1 gB in complex with D48 Fab. The side view and top view were presented. The HSV-1 gB trimer and D48 Fab VH/VL were colored differently. (B) Neutralization assay ...

In a recent study published in Communications Biology, researchers evaluated the therapeutic efficacy of Navoximod, combined with herpes simplex 1 (HSV-1) virotherapy, against hepatocellular carcinoma ...