When conducting reproducible and interference-free analysis by liquid chromatography, the purity of the solvents used, particularly the purity of water, is crucial for the sensitivity of this method, ...

The use of acidic MPAs (pH 2–4) is the default in pharmaceutical testing because they suppress silanol ionization (from Si-OH to Si-O -) and improve peak shape for basic drugs. However, highly ...

This article presents a simple and systematic approach to HPLC method development, beginning with sample preparation and finishing with practical analytical method validation. step 5 - method ...

This study developed a High-Performance Liquid Chromatography (HPLC) method for the analysis of major withanolides in ashwagandha root and commercially available supplements. System suitability ...

This is the second article in this series discussing HPLC oligonucleotide separations. This article will discuss the separation of oligonucleotides and dsDNAs using a wide-pore, polymer based reversed ...

High-performance liquid chromatography (HPLC) gives chemists access to a world of knowledge about molecules both large and small. When combined with high-resolution detection methods such as mass ...

High-performance liquid chromatography or high-pressure liquid chromatography (HPLC) is a chromatographic method that is used to separate a mixture of compounds in analytical chemistry and ...

This course is a classroom-based course covering all the practical theory about liquid chromatography and its related techniques including liquid chromatography-mass spectrometry. This course is ...

High Performance Liquid Chromatography (HPLC) is an analytical procedure for separation, identification and quantification of substances using liquid chromatography (LC). The mixture for separation is ...