A large-scale genome-wide association study (GWAS) using data from the United States Department of Veterans Affairs (VA) Million Veterans Program (MVP) – one of the largest US-based biobanks – fills ...

Background Irritable bowel syndrome (IBS) is a complex disorder of gut-brain interaction, with heterogeneous symptoms, no available biomarkers and limited pathogenetic insight. Objective To identify ...

On the left, workflow of the Identification of high-confidence risk genes for CRC via iRIGS. On the right (top), Functional characterization of predicted risk genes. On the right (bottom), Graphical ...

A genome-wide association study links genetic variants to reduced coronary flow reserve, implicating the nuclear factor kappa B pathway in coronary microvascular disease.

A new study combines genetic data and improved computational tools to look more closely at GWAS results for both adult-onset and childhood-onset asthma. The research identified many genetic variants ...

Researchers identified shared genetic loci and pathogenic mechanisms linking inflammatory bowel disease with several ...

The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While both methods are widely used, the research found that they identify different genes ...

The genome serves as the blueprint for the body, influencing every trait from the shape of the face to the arches of the feet, and even the development of certain diseases. While some disorders, like ...