The finding of intracellular, negatively birefringent, needle-shaped crystals on polarized light microscopy confirms a diagnosis of gout. Colchicine or nonsteroidal antiinflammatory drugs (NSAIDs ...

In gout, urate crystals ... Since urate crystals precipitate within the affected joint, their presence is viewable under polarized light microscopy of synovial fluid. 17 If observed, this is ...

The microscope combines polarized fluorescence technology, a valuable tool for measuring the orientation of molecules, with a dual-view light sheet ... diSPIM with liquid crystals, which allowed ...