Malignancy is associated with altered expression of glycans and glycoproteins that contribute to the cellular glycocalyx. We constructed a glycoprotein expression signature, which revealed that ...

Bottlebrush Barrier. The glycocalyx layer (purple, left) that coats brain blood vessels consists of numerous glycoproteins, glycolipids, and proteoglycans (right), including the bottlebrush-shaped ...

The glycocalyx coats BBB’s luminal surface ... and Galnt2), which are critical for mucin-domain glycoprotein production, and the upregulation of heparan sulfate metabolism genes (Hs3st1, Sdc4 ...

Cancer cells often form the glycocalyx with high levels of cell-surface mucins, which are thought to help protect the cancer cell from immune cell attack. However, a physical understanding of this ...

The starting point of their approach was the glycocalyx, a carbohydrate-rich layer that coats the cells on the surface of the intestine. Beneficial gut bacteria, which have their own matching ...

One of the ways that cancer cells hide from the body’s immune system is by forming a thin surface barrier called the glycocalyx. In a new study, researchers examined the material properties of ...