Gamma-aminobutyric acid (GABA) is synthesized by two isoforms ... We have determined the crystal structures of N-terminal truncations of both GAD isoforms. The structure of GAD67 shows a tethered ...

Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...