Full complementarity between the miRNA and ... Once Dicer produces the siRNA duplex, additional proteins are recruited to form the RNA-induced silencing complex (RISC). The Argonaute proteins ...

Scientists at UCL and the MRC Laboratory of Molecular Biology have recreated how RNA might have first replicated itself on ...

Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have ...

has just been approved to knock down transthyretin RNA for the treatment of a hereditary form of amyloidosis. These are probably just the first examples of a new pharmacopoeia of RNA-based drugs ...

The RNA polymerase enzyme is a large complex made up of multiple subunits 1. The prokaryotic form of RNA polymerase has four subunits capable of transcribing all types of RNA. In eukaryotes, these ...

The approval of yet another RNA-based ... using a form of RNA that can make copies of itself inside cells — the first ‘self-amplifying’ RNA (saRNA) granted full regulatory approval anywhere ...

This extended information comes in the form of hundreds of chemical ... Engineering and Medicine to launch a full Human RNome Project, sequencing human RNA. “The Warren Alpert Foundation is ...

The discovery of the nucleobase uracil is a big step forward for astrobiology. One of the four nucleobases of RNA has been discovered in samples retrieved from the asteroid Ryugu, providing the ...

In a common form of RNA editing, an adenosine becomes an inosine through a reaction that removes an amino group and replaces it with an oxygen (arrows). The illustration shows an ADAR enzyme ...