Thus, apoptosis serves as a powerful selective pressure ... have evolved and learned to cope with viral evasion. You have full access to this article via your institution. In contrast, the ...

Evasion of apoptosis, programmed cell death, is another cancer hallmark. While studies of venetoclax, a potent and selective inhibitor of the anti-apoptotic protein BCL2, have revealed impressive ...

The constant exposure of HCMV to the innate immune system makes this virus evolve a rich arsenal of immune evasion strategies. In addition to innate immunity, apoptosis also acts as an important ...

These dimerized complexes activate key downstream pathways, such as MAPK and PI3K/Akt, both essential in cancer cell growth and evasion of apoptosis. Overexpression or mutation of HER3 in tumor ...

One of the main hallmarks of cancer is the evasion of apoptosis, which results in immortal cells that evade cellular death. Therefore, it has recently been suggested that activation of necroptosis ...