When they exposed healthy fish to estrogen, they found it reproduced the same gut defects seen in the NOD2 mutants. Interestingly, they were able to reverse the gut damage in NOD2 mutants using an ...

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...

Researchers discover that estrogen can turn on pain signals associated with conditions like irritable bowel syndrome. Women are dramatically more likely than men to suffer from irritable bowel ...

The researchers suggest their results indicate the estrogen signaling pathway is worth investigating further. Professor Edan Foley, from the Centre for Evolution in the University's Department of Life ...