but possess a tertiary structure that allows them to bind to the estrogen receptor. Although some members of this class of drugs have been available for decades, their tissue-specificity in humans ...

Hormone levels fluctuate like the tides, ebbing and flowing according to carefully orchestrated cycles. These hormones not only influence the body, but can cross into the brain and shape the behavior ...

Recently, researchers at UC Santa Barbara used modern laser microscopy techniques to observe how fluctuations in ovarian hormones shape both the structure and function of neurons in the mouse ...

Phase I and Pharmacokinetic Study of a New Taxoid, RPR 109881A, Given as a 1-Hour Intravenous Infusion in Patients With Advanced Solid Tumors ABSTRACT: The sex hormone estrogen is important for many ...

selective estrogen receptor modulators are required. Structure-based virtual screening is an effective method for finding bioactive ligands with a novel scaffold. In fact, virtual screening was ...