Association of total neoadjuvant therapy sequencing with surgical intervention and overall survival in locally advanced rectal cancer: An NCDB analysis. Neoadjuvant therapy with mFOLFOXIRI combined ...

Guides typically assist tourists with directions, but the experience could be greatly enhanced if they offered personalized services tailored to individual interests. Recently, researchers have ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

An innovative CRISPR-Cas12f-based activator system may hold significant potential in the future of gene therapy and biological research, suggest researchers of a new study. The study highlights the ...

Edward Chuong and Atma Ivancevic at the BioFrontiers Institute. (Credit: Glenn Asakawa/CU Boulder) Peek inside the human genome and, among the 20,000 or so genes that serve as building blocks of life, ...

A new genome editing tool—minimal versatile genetic perturbation technology (mvGPT)—can achieve simultaneous and orthogonal gene editing and gene regulation in human cells. The coming together of ...

Peek inside the human genome and, among the 20,000 or so genes that serve as building blocks of life, you'll also find flecks of DNA left behind by viruses that infected primate ancestors tens of ...

The Mystery Gene That Won't Reveal Its Secrets One particular family of these viral remnants has researchers especially puzzled. Known as HERV-K (Human Endogenous Retrovirus type K), this group ...

Peek inside the human genome and, among the 20,000 or so genes that serve as building blocks of life, you’ll also find flecks of DNA left behind by viruses that infected primate ancestors tens of ...

Notably, the endogenous retrovirus they studied appears to switch on genes in what is known as the MAP-kinase pathway, a famed cellular pathway that is adversely rewired in many cancers. Existing ...