Healio

Ellipsoid zone faces challenges as trial endpoint

Please provide your email address to receive an email when new articles are posted on . “It is exciting that the FDA at least has indicated that the status of the photoreceptors, their preservation ...
Healio

Machine learning proves effective in measuring ellipsoid zones

Please provide your email address to receive an email when new articles are posted on . Novel machine-learning using ellipsoid zone area defect revealed a correlation of improvement in mean visual ...
Business Insider

Stealth BioTherapeutics Announces Positive End-of-Phase 2 Meeting with FDA on the Development of Elamipretide in Patients with Dry Age-related Macular Degeneration

Elamipretide showed favorable effect on photoreceptor integrity (ellipsoid zone attenuation) and visual function (low light - best corrected visual acuity) Positive end-of-phase 2 FDA meeting ...
FierceBiotech

Stealth stumbles again as age-related macular degeneration joins list of clinical trial flops

Stealth BioTherapeutics’ elamipretide has flopped again. The latest setback saw the mitochondria-targeted peptide fail to beat placebo in a phase 2 clinical trial in geographic atrophy (GA), an ...
technologynetworks

Deep Learning Approach Analyzes Vision Loss in Stargardt Disease

National Eye Institute researchers developed and validated an artificial-intelligence-based method to evaluate patients with Stargardt, an eye disease that can lead to childhood vision loss. The ...