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Such transport is a constitutive phenomenon that occurs throughout the life of the neuron. Thus, the axonal cytoskeleton is best understood by considering both its anatomical organization and its ...
The neuronal actin cytoskeleton is an essential target of the multiple stimuli that act on each individual neuron, and the small Rho GTPases are essential components that link these stimuli to actin.
Researchers have identified a distal axonal cytoskeleton as the boundary that ... sodium and potassium ion channels and maintaining the neuron's proper organization (polarity).
Researchers introduced three TRIO gene variants into mice, showing how each mutation led to brain size reduction and altered ...
The study, which has now been published in the journal Neuron, shows that an enzyme ... it controls the structure of the cytoskeleton and thus ensures that nerve cells can form the tree-like ...
This enabled Victor Macarrón-Palacios to investigate the neural cytoskeleton in his doctoral thesis. These discoveries were further complemented by biochemical techniques and the expertise and ...
The role played by the actin cytoskeleton of these compartments and how it responds in the presence of beta-amyloid peptides, the component most commonly associated with Alzheimer's, have been ...
Is there a difference in brain structure between men and women? If we were to find such a difference in a single neuron, would it matter? One of the most useful models for studying these questions ...