The study, published in ACS Medicinal Chemistry Letters, introduces new drug delivery concepts using ionic and covalent molecular level forces. The human body is composed of numerous types of ...

Covalent drugs block protein function by forming a specific bond between the ligand and target protein. A covalent mechanism of action can provide many pharmacological advantages over a reversible ...

More information: Tobias Pausch et al, Fluorinated Squareimines for Molecular Sieving of Aromatic over Aliphatic Compounds, Angewandte Chemie International Edition (2024). DOI: 10.1002/anie.202418877 ...

Terremoto Biosciences will use a $75 million series A funding round to leverage breakthroughs in chemistry to broaden the covalent drug alphabet available to treat complex diseases. Proceeds from ...

WALTHAM, Mass.--(BUSINESS WIRE)-- Avila Therapeutics™, Inc., a biotechnology company developing targeted covalent drugs, announced today that it has initiated a phase 1 clinical trial to assess ...