Increasing the temperature gradually shifts the equilibrium between the closed and open conformations ... upstream from the SD site, but complex RNA structures might occlude the RBS.

Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have ...

New methods to shape RNA molecules ... have a closed-loop structure that renders them more resistant to degradation. The problem is that existing methods for creating circular RNAs are complex ...

Chemists have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth -- a key process in the origin of life.

Unlike their linear counterparts, circular RNAs (circRNAs) have a closed-loop structure and ... a complete understanding of how this complex RNA machinery specifies neuron and synapse identity.

The research work forms the potential basis for more complex RNA machinery. The results are published in Nature ...

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely ...

In an RNA world, the standard theory says, life could have existed as complex proto-RNA strands that were able to both copy themselves and compete with other strands. Later, these ‘RNA enzymes ...

traditional short-read RNA sequencing often fails to capture full-length RNA molecules and complex variations, such as splicing patterns, fusion transcripts, and specific chemical modifications ...

cardiovascular and other complex diseases. The success of COVID-19 vaccines has highlighted the potential of mRNA-based therapies, which selectively manipulates how genes relay a function. RNA ...