DNA inside human cells is not just floating around freely. It is tightly wrapped around small proteins, forming a long chain.

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions. Japanese researchers have revealed how changes in chromatin accessibility—how DNA ...