Proteins are made of amino acid chains, or polypeptides. Amino acids have a basic backbone made of an amino group and a carboxyl group, and differ in their side-chains. These polypeptide chains of ...

Our overall hydrogen bond patterns could be used to annotate protein secondary and tertiary structure, which may lead to a valuable and robust new classification of protein folds 11,20.

A major limitation with the existing PEGylated proteins is their heterogeneous nature. This is because PEG is conjugated at many different nucleophilic amine residues in the protein 4,5,6.

which are linked together by peptide bonds and folded into specific three-dimensional structures. Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding ...

These rRNAs play a role in peptide bond formation and translocation. The rRNA molecules fold into complex secondary and tertiary structures ... binding sites for ribosomal proteins, which help ...

Raman spectroscopy enables monitoring of the changes in secondary and tertiary protein structure. The combination of DLS and Raman spectroscopy allows measurement of protein size and structure from a ...