Neurofilament proteins are the major scaffolding proteins of axons. On neuronal damage ... of early neurological deterioration than either tau or amyloid." The study was published online November ...

As the KLC1-negative animals aged, they exhibited axonal degeneration in the corpus callosum and anterior commissure, as well as increased neurofilament ... tau troubles. A panel of antibodies to ...

Neurons in the CNS extend axons over considerable distances ... monoclonal MAP2 1:1000 (Sigma), polyclonal tau 1:500 (gift of L. Binder), neurofilament H 1:200 (Chemicon), Myelin basic protein ...