AUTOPHAGY IS A hot topic on TikTok, with videos tagged #autophagy racking up nearly 35 million views. People are likely talking so much about autophagy because the subject is closely linked to the ...

A new study reveals that age-related autophagy decline blocks embryo development by triggering a lipid-burning crisis.

There are three main types of autophagy in mammalian cells: macroautophagy, microautophagy, and chaperone-mediated autophagy (CMA). Each of these pathways converges in lysosomes to ensure ...

Lysosomes contain hydrolytic enzymes which cause the degradation of the contents transported by the autophagosome. The resultant macronutrients are recycled for use in the cytosol during starvation.

In a consensus article, Federico Pietrocola, at the Department of Biosciences and Nutrition, KI, and colleagues explore the pathophysiological relevance of autophagy in human illnesses, while ...

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. Scientists have now uncovered possible novel functions for various autophagy genes, which may control ...

At the beginning of 2017, Keith Dionne was looking for the next big idea in biotech. He had just joined the life sciences–based venture capital firm Third Rock Ventures, and the investors there were ...