and mismatch repair (MMR), respond to alkylation damage to defend against alkylation-induced cell death or mutation. However, maintaining a proper balance of activity both within and between these ...

Using a predictive model, the researchers identified the KRAS and PIK3CA genes as potential targets of alkylation-induced mutation. Consistent with this prediction, they found that colorectal ...

“Targeted elimination of mutated mitochondrial DNA by a multi-functional conjugate capable of sequence-specific adenine alkylation.” “Mutations in mitochondrial DNA (mtDNA) cause ...

By utilizing STRATCO ® technology, the alkylation complex promises outstanding environmental benefits, ensuring compliance with stringent regulations while maintaining exceptional performance ...