The partnership unites OmniAb's transgenic antibody discovery solutions with Veraxa's ADC linker technology and conjugation expertise to propel next-generation therapeutic discovery. Veraxa will ...

The different elements of an ADC, including the antibody, the cytotoxin, and the linker can greatly affect partitioning of the ADC and the cytotoxin into the different tissues, and the incorporation ...

It is the second ADC licensed by Ipsen ... intelligence-powered screening platform, and the ADC also features an “innovative, stable, and cleavable linker coupled to a potent topoisomerase ...

That hyphen stands for the chemical linker that ties an ADC’s tumor-targeting antibody to its cytotoxic drug. While linkers may seem like little more than chemical tethers, ADC makers are ...

The new bioconjugation site completes the CDMO’s capabilities across payload, linker, and Mab, with onboarding set to start ...

The collaboration brings together OmniAb’s suite of transgenic antibody discovery solutions with Veraxa’s proprietary antibody drug conjugate (ADC) linker technology and conjugation expertise to ...

Investments in linker and conjugation technologies have become the single-biggest area of investments within the ADC field, showing how they are being used as key levers for ADC drug developers to ...

Data supporting the rationale for Baylink's innovative ADC linker technology enabling delivery of degraders, dual payload antibody drug conjugates, and high drug to antibody ratio chemotherapy ...

In 2018, Han cofounded ProfoundBio. The lawsuit claims Han was aware Gavrilyuk’s work at AbbVie “involved precisely the type of ADC linkers” ProfoundBio needed. According to the lawsuit ...

Ipsen is back with its second antibody-drug conjugate (ADC) deal of the year ... The candidate in question, dubbed FS001, uses a cleavable linker coupled to a potent topoisomerase I (Topo1 ...

ADCs are designed to selectively deliver cytotoxic drugs (payloads) to cancer cells by attaching them to antibodies that bind specifically to cancer cells through linkers. Foundational to its approach ...