Lionel Messi is expected to play as Inter Miami faces Sporting San Miguelito in Panama City, Panama at 5 p.m. ET. Here's what you need to know.

Inter Miami remained unbeaten in its first three games under new coach Javier Mascherano with a 3-1 preseason victory over Sporting San Miguelito in Panama on Sunday night.

Inter Miami continues its squad restructuring plan by targeting players under 30 who can add both quality and long-term value to Lionel Messi's team. As part of this strategy, the club has strengthened its defense with a standout performer from the Copa Libertadores.

The preseason match, which kicks off at 5 p.m., is the third in the club’s Americas Tour, which also includes a game against Olimpia in Honduras next Saturday. Miami won its first two preseason games in penalty kick shootouts against Mexican team Club America and Universitario of Peru.

Lionel Messi is set to lose an Argentine teammate as part of Inter Miami's squad restructuring under head coach Javier Mascherano.

It's pretty clear Messi and Inter Miami weren't satisfied with how 2024 went. But improving on their one major trophy win in 2025 is far from a guarantee.

MLS Franchise Valuation Rankings saw Inter Miami rise in the standings as Lionel Messi's impact continues to be felt across Major League Soccer.

Argentina's coach Javier Mascherano addressed the media and confirmed that Inter Miami, led by Lionel Messi, is set to welcome at least one new addition to the squad. Javier Mascherano is already looking ahead to Inter Miami‘s third preseason friendly against Sporting San Miguelito from Panama this Sunday.